The Weight Loss Retatrutide 30mg Premium Pre-Filled Pen – Triple agonist peptide for advanced weight loss. Cutting-edge fat burning technology. 
How does retatrutide work?
Retatrutide is called a ‘triple G’ drug because it targets three different hormone receptors at the same time: GLP-1, GIP, and glucagon. This triple action is what sets it apart from other weight loss medications currently available:
GLP-1 (glucagon-like peptide-1) Receptor Agonist
This is the same hormone targeted by medications like Ozempic and Wegovy, and it helps you feel full after eating and slows down how quickly food leaves your stomach. It also helps regulate blood sugar levels.
GIP (glucose-dependent insulinotropic polypeptide) Receptor Agonist
Mounjaro also targets the hormone alongside GLP-1, which helps with feeling full and blood sugar control, but it works slightly differently from GLP-1. It’s particularly good at helping your body respond better to insulin.
Glucagon Receptor Agonist
This is the new addition that makes retatrutide unique. Glucagon normally tells your liver to release stored sugar, but when blocked in a controlled way, it can help increase your metabolism and encourage your body to burn more fat.
How much weight can I lose on retatrutide?: Clinical Trials & Weight Loss Results
The weight loss results from retatrutide clinical trials have been impressive, though it’s important to remember these are still early-stage studies with relatively small groups of participants.
The phase 2 trial followed participants for 48 weeks (nearly a year). People taking the highest dose of retatrutide lost an average of 24% of their starting body weight – that’s nearly a quarter of their total weight.
To put this in perspective, if someone weighed 100kg (about 15.7 stone) at the start, they could potentially lose around 24kg (nearly 4 stone) on average.
What are the side effects of retatrutide?
Since retatrutide is still in clinical trials, we don’t have complete information about all possible side effects yet. However, based on the studies conducted so far, the side effects appear similar to other weight loss injections, but potentially more intense due to its triple action.
The most common side effects reported in trials include:
Digestive issues
Nausea (the most frequently reported side effect)
Vomiting
Diarrhoea
Constipation
Stomach pain or discomfort
Loss of appetite
Other reported effects
Fatigue or tiredness
Injection site reactions (redness, swelling, or irritation)
Most side effects tend to be worse when starting the medication or increasing the dose, and often improve as your body adjusts. In clinical trials, many people found that starting with a lower dose and gradually increasing it helped reduce these effects.
It’s worth noting that because retatrutide targets three hormone pathways instead of one or two, some people in trials experienced more pronounced digestive side effects compared to other weight loss medications. But this will be different from person to person.
Who can use retratrutide?
Since retatrutide is still in clinical trials and not yet approved for public use, we can only discuss the criteria used in current studies and what might be expected when it becomes available.
In the clinical studies so far, participants have generally needed to meet these requirements:
BMI of 30 or above (classified as obese), or BMI of 27 or above with weight-related health conditions like type 2 diabetes, high blood pressure or dyslipidemia 
Adults aged 18 and over
No history of certain medical conditions like pancreatitis or severe kidney disease
Not pregnant or breastfeeding
What is the dosing schedule of retratrutide, and how is it administered?
In clinical trials, retatrutide has been given as a weekly injection under the skin (subcutaneous). It will likely be sold as a pre-filled injectable pen, similar to other weight loss injections.
Starting with a low dose and gradually increasing over several weeks, the typical starting dosage is around 1mg per week, potentially increasing to 12 mg per week.
The gradual dose increase helps reduce side effects, particularly the common digestive issue, when starting treatment.
Is retatrutide better than other weight loss injections?
While the early results from retatrutide trials look promising, direct head-to-head comparisons haven’t been done yet. What we can do is look at the separate trial results and see how they stack up.
Based on the clinical trial data available, retatrutide appears to offer superior weight loss compared to existing options.